A truck crashes into an unnamed female cop, 56, as it charged towards a line of officers before 1am on Tuesday.
Among the multiple injuries sustained by the policewoman was a broken leg, local media reports.
Demonstrators began throwing bricks, trash cans and other objects at officers during the chaos which included fires being lit on the streets.
The violent unrest was sparked by the shooting of Walter Wallace Jr, 27, by police at 4pm on Monday.
Wallace, whose family say had mental health issues, was filmed chasing after two officers holding a knife.
He was gunned down in the streets in front of horrified onlookers after he refused to drop the blade.
The 27-year-old was taken to a nearby hospital where he was pronounced dead yesterday.
His death comes five months after the killing of another black man George Floyd in Minneapolis which sparked protests across the US and the world.
In the footage, filmed by a local man, Wallace is shown charging at two officers who back away from him with their guns drawn.
One cop says: "Put the knife down, put the knife down."
Truck runs over female cop amid brutal BLM clashes in Philadelphia after officers shot dead knife-wielding black man
From Brexit breaking news to HD movie trailers, The Sun newspaper brings you the latest news videos and explainers from the UK and around the world.
Become a Sun Subscriber and hit the bell to be the first to know
Read The Sun: http://www.thesun.co.uk
Like The Sun on Facebook: https://www.facebook.com/thesun/
Follow The Sun on Twitter: https://twitter.com/TheSun
Subscribe to The Sun on Snapchat: https://www.snapchat.com/discover/The_Sun/1633225139