ABC News Live: William Shatner and Blue Origin are headed to space on Wednesday.

Plus, the U.S. is celebrating Indigenous Peoples’ Day and Selma Blair opens up about her battle with multiple sclerosis.

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TikTok content creators say they are burntout trying to keep up with changing trends.

TikTok content creators say they are burntout trying to keep up with changing trends.

Brooklynne Webb, a 17-year-old TikToker, says that the app has affected her mental health. More seasoned content creator Zach King says he has conquered burnout by putting creativity above clout.

'Industry guidelines were not being followed': Hollywood veteran on shooting.

'Industry guidelines were not being followed': Hollywood veteran on shooting.

ABC News' Stephanie Ramos speaks with veteran Hollywood armorer Larry Zanoff, who explains the protocols around handling guns on movie sets and how accidental shootings can occur.

Trailblazing judge on her life on the bench and ideas for reform.

Trailblazing judge on her life on the bench and ideas for reform.

ABC News' Stephanie Ramos speaks with Judge Ladoris Hazzard Cordell about her new book "Her Honor: My Life on the Bench: What Works, What's Broken, and How to Change It."

Siberia's rapidly melting permafrost is changing the landscape.

Siberia's rapidly melting permafrost is changing the landscape.

ABC News' Patrick Reevell reports on the melting permafrost in some parts of Russia that's putting roads and buildings at risk of collapse, and may contribute to more greenhouse gases.

Police respond to reports of shots fired at Idaho mall.

Police respond to reports of shots fired at Idaho mall.

Authorities said there are multiple reports of injuries and one person is in custody. Officials said they are working to clear each business in the mall.