Coronavirus Patients Can Be Categorised Into Three Groups, Say Scientists.

Coronavirus Patients Can Be Categorised Into Three Groups, Say Scientists

Close to 60 per cent of patients in the research presented with what researchers called "phenotype II"

Washington:

Scientists have identified three different types of COVID-19 disease traits in patients, depending on their comorbidities, complications, and clinical outcomes, an advance that may help target future interventions to the most risk-prone individuals.

The new study, published in the journal PLOS ONE, analysed the electronic health records (EHRs) from 14 hospitals in the midwestern US and from 60 primary care clinics in the state of Minnesota.

According to the researchers, including those from the University of Minnesota in the US, the study included 7,538 patients with confirmed COVID-19 between March 7 and August 25, 2020, of which 1,022 patients required hospitalisation.

Close to 60 per cent of the patients included in the research presented with what the researchers called "phenotype II."

They said about 23 per cent of the patients presented with "phenotype I," or the "adverse phenotype," which was associated with the worst clinical outcomes.

The researchers said these patients had the highest level of comorbidies related to heart and kidney dysfunction.

According to the study, 173 patients, or 16.9 per cent presented with "phenotype III," or the "favorable phenotype," which the scientists said was associated with the best clinical outcomes.

While this group had the lowest complication rate and mortality, the scientists said these patients had the highest rate of respiratory comorbidities as well as a 10 per cent greater risk of hospital readmission compared to the other phenotypes.

Overall, they said phenotypes I and II were associated with 7.30-fold and 2.57-fold increases in hazard of death relative to phenotype III.

Based on the results, the scientists said such phenotype-specific medical care could improve COVID-19 outcomes.

However, they believe further studies are needed to determine the utility of these findings in clinical practice.

"Patients do not suffer from COVID-19 in a uniform matter. By identifying similarly affected groups, we not only improve our understanding of the disease process, but this enables us to precisely target future interventions to the highest risk patients," the scientists added.

NDTV News

NDTV.com provides latest news from India and the world. Get today’s news headlines from Business, Technology, Bollywood, Cricket, videos, photos, live news coverage and exclusive breaking news from India.

https://www.ndtv.com/

Related news
BAFTA praised for diverse set of nominees

BAFTA praised for diverse set of nominees

BAFTA has been praised for the diversity of this year's list of nominees which includes a record number of female and non-white people in line for awards. Four women have been nominated for Best Director and 16 of the 24 acting nominees this year ...

COVID-19: Shops and pubs prepare to reopen

COVID-19: Shops and pubs prepare to reopen

Retailers across England hope pent-up demand will bring people back to the shops after a year of restrictions and closures. Sky News videos are now available in Spanish here/Los video de Sky News están disponibles en español aquí SUBSCRIBE to our ...

Mozambique: How a massacre unfolded

Mozambique: How a massacre unfolded

More than two weeks on from the terror attack in the town of Palma in Mozambique, around 20-thousand people remain unaccounted for. The country's authorities have sent hundreds of soldiers into the town and have declared it free of terrorists, but...

1

41 gun salutes held across the UK to mark the death of Prince Phillip.

41 gun salutes held across the UK to mark the death of Prince Phillip.

GUN salutes took place across the UK to mark the death of the Duke of Edinburgh. The Tower of London and Royal navy warships led the 41 gun salutes on Saturday, April, 10, 2021. In a statement on the royal website, it was said: "The tradition of G...

Myanmar activists take revolution offline - DW News.

Myanmar activists take revolution offline - DW News.

The brutal military crackdown on Myanmar's pro-democracy protesters continues, with more than 80 killed on Saturday according to local media. Authorities regularly shut down internet access. That's forced activists to return to old fashioned metho...

Alaska filing lawsuit to restart cruising? Could be 'real possibility'.

Alaska filing lawsuit to restart cruising? Could be 'real possibility'.

Gov. Mike Dunleavy discusses Alaska's economic recovery, and the need to restart its cruise industry. #FoxNews Subscribe to Fox News! Watch more Fox News Video: ​ Watch Fox News Channel Live: FOX News Channel (FNC) is a 24-hour all-encompassing ne...