Global News

Breaking news & current latest Canadian news headlines; national weather forecasts & predictions, local news videos, money and financial news; sports stats and scores.

https://globalnews.ca/

Animal tranquillizer xylazine is now in Canada’s street drug supply.

Click to play video: 'Deadly veterinary sedative suspected in Peterborough opioid drug supply: health unit'

It's called Xylazine, a veterinary sedative and pain reliever that is not approved for human use. Recently, it has made its way into Canada's unregulated drug supply, prompting a warning from the Canadian Centre for Substance Use and Addiction. Jocelyn Qualtrough of Peterborough Public Health joined Noor Ibrahim to explain the dangers of this drug, and what the public should watch for – Jul 28, 2022

A powerful animal tranquillizer that has been infiltrating street drugs in the United States has been increasingly showing up in Canada’s illicit opioid supply — a phenomenon that has experts “deeply concerned.”

Xylazine, a sedative and analgesic normally used in veterinary medicine to sedate large animals such as cattle or horses, has been wreaking havoc in parts of the U.S., notably in Philadelphia, where it was found in 90 per cent of dope samples tested in the city in 2021, according to data released by Substance Use Philadelphia.

The presence of xylazine in opioids in the U.S. prompted a warning from the U.S. FDA in November 2022, alerting health-care professionals to “increasing reports of serious side effects” from the drug, known as “tranq.”

The Canadian Community Epidemiology Network on Drug Use (CCENDU) issued its own alert last July identifying the emerging presence of xylazine in a small number of opioid samples tested in B.C., Manitoba, Ontario, Quebec and Nova Scotia.

Since then, its presence in Canada has grown, according to drug test samples and coroner’s reports in B.C. and Ontario.

Karen McDonald, the lead for Toronto’s Drug Checking Service, says the drug first started showing up in Canada’s unregulated opioid supply in September of 2020, but since then its presence in the fentanyl supply has increased.

“Earlier this year we were finding xylazine in about 20 per cent of the fentanyl samples that we were checking,” she said.

While that number has since decreased to about six per cent of recent samples, McDonald says most people who end up with tranq in their fentanyl don’t know it’s there.

“Our understanding was that most folks in Toronto were not choosing to use xylazine, it was just kind of being cut into their drugs unknowingly. So it certainly is a problem.”

Repeated xylazine exposure can cause significant harm. It does not respond to naloxone — a medication that can reverse the effects of opiates — and makes overdoses from opioids mixed with this sedative more challenging to treat, McDonald said.

People who have taken drugs containing xylazine can also develop severe, necrotic skin ulcers, according to the U.S. Food and Drug Administration. These sores have led to amputations among some repeated users in the U.S., according to a report earlier this week in the New York Times .

Dr. Paxton Bach, an addiction medicine specialist at St. Paul’s Hospital in Vancouver and the co-medical director of the BC Centre on Substance Use, says the drug has been showing up in British Columbia’s drug supply, although not to the extent that it has in the U.S.

He estimates about five per cent of opioids being tested in B.C. recently have xylazine in them, but added that it’s still unclear what this will mean for those like him who treat people dealing with drug addiction, overdose and withdrawal.

“The effects of that in a drug supply are still not fully known. But it leads to the increasing unpredictability of any given sample of drugs and can lead to really profound effects for people who are using the drugs — blackouts, loss of memory and other medical consequences,” he said.

Bach also highlighted the particularly troublesome side effect of slow-healing skin lesions.

“I expect we’re going to start to see more of that in Canada,” he said.

“(I’m) deeply concerned. The speed at which the drug supply is evolving is outstripping our response.”

Trying to determine how prevalent xylazine is in Canada is not easy to answer, however, as the situation is different across the country, said Doris Payer, an addiction neuroscience expert and knowledge broker for the Canadian Centre on Substance Use and Addiction.

In some cases, it may be that xylazine hasn’t made its way into some provinces or territories, but it’s also true that drug testing, monitoring and surveillance varies across the country, Payer said.

“There’s no blanket statement we can make, but we have seen it,” she said.

“It is around … it’s just hard to know what’s going on.”

Another complicating factor in identifying its prevalence is that xylazine is not readily identified by routine toxicology screens and therefore may be under-detected, according to the FDA.

Additional testing techniques are required to detect xylazine in specimens like blood or urine, the U.S. agency said in a letter to stakeholders last November providing clinical information about risks of the drug.

“Even with appropriate testing, overdoses involving xylazine may be underdiagnosed due to xylazine’s rapid elimination from the body, with a half-life of 23-50 minutes,” the FDA letter stated.

While some people may be taking street fentanyl not knowing xylazine has been cut into it as a filler, others are actually seeking it out, Payer added.

“According to our CCENDU representatives, some people seek out xylazine because it can change the effects of, let’s say, fentanyl or something that they’re intending to take,” she said.

“But many also take it unintentionally just because it’s in the unregulated market and people just aren’t aware that it’s in the samples that they’re using.”

Experts and front-line workers have been raising alarm about Canada’s drug supply becoming more toxic and unpredictable, due to an increasing trend of opioids like fentanyl and heroin being mixed with other drugs, including benzodiazepines and xylazine.

The presence of these powerful sedatives in the opioid supply means naloxone is not fully effective, as this antidote does not work on benzos or xylazine.

Global News requested a comment from the Public Health Agency of Canada (PHAC) for this story but did not receive a response in time for publication.

FentanylOpioid CrisisOverdoseNaloxonetoxic drug supplyXylazineopioid side effectsfentanyl xylazinewhat is xylazinexylazine Canadaxylazine deathsxylazine side effectsxylazine soresxylazine U.S.

Journalistic standards Report an error

© 2023 Global News, a division of Corus Entertainment Inc.

Особистий тайм-менеджмент або як управляти своїм часом.
Останні новини
Ukrainian forces repel 13 enemy attacks in past day.

Ukrainian forces repel 13 enemy attacks in past day.

Ukraine's defense forces have repelled attacks by Russian invaders outside 13 settlements in the Donetsk and Luhansk regions over the past 24 hours. They hit three enemy command posts, eight Russian positions and two ammunition depots.

UkrInform

Tim Scott: This is the only way to be successful

Tim Scott: This is the only way to be successful

Sen. Tim Scott, R-S.C., joins 'One Nation with Brian Kilmeade' to discuss Iowa's governor signing a school choice bill, claiming the future of our nation is in the hands of the 'educated and uneducated.' #FoxNews Subscribe to Fox News! Watch more ...

America's homeless crisis has gone from bad to worse: Lawrence Jones.

America's homeless crisis has gone from bad to worse: Lawrence Jones.

Fox News host Lawrence Jones speaks to East County Transitional Living Center CEO Michael Branch to seek answers to America's homeless crisis on this week's 'Cross Country.' #foxnews Subscribe to Fox News! Watch more Fox News Video: Watch Fox News...

Grenfell fire: Michael Gove says govt partially to blame.

Grenfell fire: Michael Gove says govt partially to blame.

Housing secretary Michael Gove has told Sophy Ridge ambiguous building regulations “exploited by people who put profits before lives” were a factor in the Grenfell fire tragedy. He said said he “absolutely wanted to apologise” to the relatives of ...

BREAKING: Nadhim Zahawi sacked by Sunak

BREAKING: Nadhim Zahawi sacked by Sunak

Conservative party chairman Nadhim Zahawi has been sacked from his role over a "serious breach of the ministerial code". Live updates: #grenfelltower #sophyridge #borisjohnson #michaelgove SUBSCRIBE to our YouTube channel for more videos: Follow u...

Are Florida Students Getting the Full Story?

Are Florida Students Getting the Full Story?

Earlier this month, the state of Florida announced it would block reject a proposed Advanced Placement course on African American Studies. The move follows laws passed in Florida and other Republican-led states aimed at restricting certain race-ba...

Nadhim Zahawi sacked as Tory chairman over tax affairs row.

Nadhim Zahawi sacked as Tory chairman over tax affairs row.